Inside the Cell
نویسندگان
چکیده
منابع مشابه
Looking inside the cell
Advances in imaging techniques have shed new light on the structure of vesicles formed by COPI protein complexes.
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The eukaryotic nucleus is highly dynamic and complex, containing several subcompartments, several types of DNA and RNA, and a wide range of proteins. Interactions between these components within the nucleus form part of a complex regulatory system that is only partially understood. Rapid improvements in proteomics applications have led to a better overall determination of nucleus protein conten...
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Cells communicate with each other to form organized structures by cell-cell adhesion and cell-cell repulsion, but it remains to be clarified how cell-cell contact information is converted into intracellular signals. Here, we show that cells in contact with neighbouring cells generate local transient intracellular Ca(2+) signals (Ca(2+) lightning). Ca(2+) lightning was observed near cell-cell co...
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The mean time required by a transcription factor (TF) or an enzyme to find a target in the nucleus is of prime importance for the initialization of transcription, gene activation or the start of DNA repair. We obtain new estimates for the mean search time when the TF or enzyme, confined to the cell nucleus, can switch from a one dimensional motion along the DNA and a free Brownian regime inside...
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Figure 1. Strategies and molecular mechanisms for the involvement of peroxisomes in development, differentiation, and morphogenesis. See text for details. The peroxisome and the nucleus are colored blue and green, respectively. ABC, ATP-binding cassette; HDAC1, histone deacetylase 1; PPAR, peroxisome proliferatoractivated receptors; RAR, retinoic acid receptor; ROS, reactive oxygen species, inc...
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ژورنال
عنوان ژورنال: Nature
سال: 1967
ISSN: 0028-0836,1476-4687
DOI: 10.1038/214069a0